@conference {940, title = {Evaluation of the burden of migraine on the partners lifestyle: a multicenter study}, booktitle = {International Headache Congress 2021}, year = {2021}, month = {2021}, publisher = {International Headache Society \& European Headache Federation}, organization = {International Headache Society \& European Headache Federation}, address = {Virtual Congress}, abstract = {

Objective: Migraine is a highly disabling disease that affects the patient{\textquoteright}s life, but its consequences on the patient{\textquoteright}s partner have been barely studied. The objective was to analyze these effects on romantic relationship, relationship with their children, friendship and work; as well as to evaluate caregiver burden and the presence of anxiety and/or depression.
Methods: Cross-sectional observational study. An online survey was filled by partners of migraine patients from five Spanish Headache Units. Questions about the four assessed areas and two scales to evaluate anxiety, depression and caregiver burden (Hospital Anxiety and Depression Scale and Zarit scale) were included. The presence of anxiety and depression was compared to the Spanish prevalence (6.7\% in both cases).
Results: Out of 176 registered responses, 155 were accepted. The sample included 86.5\% of women, with mean age 44.2 +- 10.4 years. Effects on partners were found on love relationship and items concerning children and friendships, with a minor impact at work. Partners showed a significant moderate burden according to the Zarit scale (p = 12/155 = 0.077 [0.041-0.131]; p \< 0.001) and a higher anxiety rate than the 6.7\% national prevalence (p = 23/155 = 0.148 [0.096-0.214]; p \< 0.001), but similar depression rate.
Conclusion: We found an impact on the patient{\textquoteright}s partners on the studied areas. Migraine is a disease that implies caregiver burden in the patient{\textquoteright}s environment with possible effect on anxiety levels.

}, url = {https://journals.sagepub.com/doi/pdf/10.1177/03331024211034005}, author = {Fern{\'a}ndez-Bermejo, Eva M and {\'A}lvaro Planchuelo-G{\'o}mez and Quintas, Sonia and Gonzalez-Martinez, Alicia and Garc{\'\i}a-Azor{\'\i}n, David and Sierra, {\'A}lvaro and {\'A}ngel L. Guerrero and Santos-Lasaosa, Sonia and Navarro-P{\'e}rez, Mar{\'\i}a P and Gonz{\'a}lez-Garc{\'\i}a, Nuria and D{\'\i}az-de-Ter{\'a}n, Javier and Ana B Gago-Veiga} } @conference {942, title = {Has onabotulinumtoxinA follow-up delay during COVID-19 lockdown affected the migraine course?}, booktitle = {International Headache Congress 2021}, year = {2021}, month = {2021}, publisher = {International Headache Society \& European Headache Federation}, organization = {International Headache Society \& European Headache Federation}, address = {Virtual Congress}, abstract = {

Objective: During the COVID-19 pandemic face-to-face procedures have been postponed. We aim to evaluate the impact of onabotulinumtoxinA follow-up delay in migraine during COVID-19 pandemic.
Methods: Subjective worsening, intensity of migraine attacks and frequency of headache and migraine were retrospectively compared between patients with unmodified and interrupted onabotulinumtoxinA follow-up in Headache Units.
Results: We included 67 patients with chronic migraine or high-frequency episodic migraine under onabotulinumtoxinA treatment, 65 (97.0\%) female,
44.5 +- 12.1 years old. Treatment administration was voluntarily delayed in 14 (20.9\%) patients and nine (13.4\%) were unable to continue follow-up. Patients with uninterrupted follow-up during lockdown presented 8.4 and 8.1 less monthly days with headache (adjusted p = 0.011) and migraine attacks (adjusted p = 0.009) compared to patients whose follow-up was interrupted, respectively.
Conclusion: Involuntary delay of onabotulinumtoxinA follow-up in patients with migraine due to COVID-19 pandemic was associated with a higher frequency of headache and migraine attacks. Safe administration of onabotulinumtoxinA during lockdown should be promoted.

}, url = {https://journals.sagepub.com/doi/pdf/10.1177/03331024211034005}, author = {Gonzalez-Martinez, Alicia and {\'A}lvaro Planchuelo-G{\'o}mez and {\'A}ngel L. Guerrero and Garc{\'\i}a-Azor{\'\i}n, David and Santos-Lasaosa, Sonia and Navarro-P{\'e}rez, Mar{\'\i}a P and Odriozola-Gonz{\'a}lez, Paula and Irurtia, Mar{\'\i}a Jes{\'u}s and Quintas, Sonia and Rodrigo de Luis-Garc{\'\i}a and Ana B Gago-Veiga} }