@proceedings {990, title = {Assessing the variability of brain diffusion MRI preprocessing pipelines using a Region-of-Interest analysis}, volume = {5015}, year = {2023}, month = {2023}, abstract = {

The lack of a standardized preprocessing pipeline is a significant source of variability that might lower the reproducibility of studies, especially across sites and with incomplete description of the preprocessing workflows. We evaluate the downstream impact of variability in preprocessing workflow by quantifying the reproducibility and variability of region-of-interest (ROI) analyses. While many pipelines achieve excellent reproducibility in most ROI, we observed a large variability in performance of preprocessing workflows to the extent that some pipelines are detrimental to the data quality and reproducibility.

}, author = {Veraart, Jelle and Winzeck, Stephan and {\'A}lvaro Planchuelo-G{\'o}mez and Fricke, Bj{\"o}rn and Kornaropoulos, Evgenios N and Merisaari, Harri and Pieciak, Tomasz and Zou, Yukai and Descoteaux, Maxime} } @article {956, title = {Anisotropy measure from three diffusion-encoding gradient directions}, journal = {Magnetic Resonance Imaging}, volume = {88}, year = {2022}, month = {2022}, pages = {38{\textendash}43}, author = {Santiago Aja-Fern{\'a}ndez and Guillem Par{\'\i}s and Carmen Mart{\'\i}n-Mart{\'\i}n and Derek K. Jones and AntonioTrist{\'a}n-Vega} } @article {934, title = {Accurate free-water estimation in white matter from fast diffusion MRI acquisitions using the spherical means technique}, journal = {Magnetic Resonance in Medicine}, volume = {87}, year = {2021}, month = {2022}, pages = {1028-1035}, type = {Techncial Note}, abstract = {

Purpose To accurately estimate the partial volume fraction of free water in the white matter from diffusion MRI acquisitions not demanding strong sensitizing gradients and/or large collections of different b-values. Data sets considered comprise 32-64 gradients near plus 6 gradients near . Theory and Methods The spherical means of each diffusion MRI set with the same b-value are computed. These means are related to the inherent diffusion parameters within the voxel (free- and cellular-water fractions; cellular-water diffusivity), which are solved by constrained nonlinear least squares regression. Results The proposed method outperforms those based on mixtures of two Gaussians for the kind of data sets considered. W.r.t. the accuracy, the former does not introduce significant biases in the scenarios of interest, while the latter can reach a bias of 5\%{\textendash}7\% if fiber crossings are present. W.r.t. the precision, a variance near , compared to 15\%, can be attained for usual configurations. Conclusion It is possible to compute reliable estimates of the free-water fraction inside the white matter by complementing typical DTI acquisitions with few gradients at a lowb-value. It can be done voxel-by-voxel, without imposing spatial regularity constraints.

}, keywords = {diffusion MRI, free water, spherical means, white matter}, doi = {https://doi.org/10.1002/mrm.28997}, author = {Antonio Trist{\'a}n-Vega and Guillem Par{\'\i}s and Rodrigo de Luis-Garc{\'\i}a and Santiago Aja-Fern{\'a}ndez} } @article {899, title = {Apparent propagator anisotropy from single-shell diffusion MRI acquisitions}, journal = {Magnetic Resonance in Medicine}, volume = {85}, year = {2021}, month = {2021}, pages = {2869-2881}, chapter = {2869}, doi = {https://doi.org/10.1002/mrm.28620}, url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/mrm.28620}, author = {Santiago Aja-Fern{\'a}ndez and Antonio Trist{\'a}n-Vega and Derek K. Jones} } @proceedings {856, title = {AMURA with standard single-shell acquisition can detect changes beyond the Diffusion Tensor: a migraine clinical study}, volume = {4549}, year = {2020}, month = {2020}, abstract = {AMURA (Apparent Measures Using Reduced Acquisitions) is an alternative formulation to drastically reduce the number of samples needed for the estimation of diffusion properties related to the Ensemble Average diffusion Propagator (EAP). Although these measures were initially intended for medium-to-high b-values, in this work we evaluate their performance in DTI-like acquisitions. Fifty healthy controls, 54 episodic migraine (EM) and 56 chronic migraine (CM) patients were compared, using a single-shell diffusion scheme at b=1000 s/mm2. We compare AMURA measures (return-to-origin, return-to-axis and return-to-plane probabilities) to traditional DTI measures. Differences between EM and controls were only detectable using the return-to-origin probability.}, author = {{\'A}lvaro Planchuelo-G{\'o}mez and Rodrigo de Luis-Garc{\'\i}a and Antonio Trist{\'a}n-Vega and Garc{\'\i}a-Azor{\'\i}n, David and {\'A}ngel L. Guerrero and Santiago Aja-Fern{\'a}ndez} } @inbook {895, title = {Alternative Diffusion Anisotropy Metric from Reduced MRI Acquisitions}, booktitle = {Computational Diffusion MRI}, year = {2020}, pages = {13{\textendash}24}, publisher = {Springer, Cham}, organization = {Springer, Cham}, author = {Santiago Aja-Fern{\'a}ndez and Antonio Trist{\'a}n-Vega and Rodrigo de Luis-Garc{\'\i}a and Derek K. Jones} } @article {891, title = {Alternative Microstructural Measures to Complement Diffusion Tensor Imaging in Migraine Studies with Standard MRI Acquisition}, journal = {Brain Sciences}, volume = {10}, year = {2020}, month = {2020}, pages = {711}, abstract = {The white matter state in migraine has been investigated using diffusion tensor imaging (DTI) measures, but results using this technique are conflicting. To overcome DTI measures, we employed ensemble average diffusion propagator measures obtained with apparent measures using reduced acquisitions (AMURA). The AMURA measures were return-to-axis (RTAP), return-to-origin (RTOP) and return-to-plane probabilities (RTPP). Tract-based spatial statistics was used to compare fractional anisotropy, mean diffusivity, axial diffusivity and radial diffusivity from DTI, and RTAP, RTOP and RTPP, between healthy controls, episodic migraine and chronic migraine patients. Fifty healthy controls, 54 patients with episodic migraine and 56 with chronic migraine were assessed. Significant differences were found between both types of migraine, with lower axial diffusivity values in 38 white matter regions and higher RTOP values in the middle cerebellar peduncle in patients with a chronic migraine (p \< 0.05 family-wise error corrected). Significantly lower RTPP values were found in episodic migraine patients compared to healthy controls in 24 white matter regions (p \< 0.05 family-wise error corrected), finding no significant differences using DTI measures. The white matter microstructure is altered in a migraine, and in chronic compared to episodic migraine. AMURA can provide additional results with respect to DTI to uncover white matter alterations in migraine.}, issn = {2076-3425}, doi = {10.3390/brainsci10100711}, url = {https://www.mdpi.com/2076-3425/10/10/711}, author = {{\'A}lvaro Planchuelo-G{\'o}mez and Garc{\'\i}a-Azor{\'\i}n, David and {\'A}ngel L. Guerrero and Rodrigo de Luis-Garc{\'\i}a and Rodr{\'\i}guez, Margarita and Santiago Aja-Fern{\'a}ndez} } @article {868, title = {Automatic non-destructive video estimation of maturation levels in Fuji apple (Malus Malus pumila) fruit in orchard based on colour (Vis) and spectral (NIR) data}, journal = {Biosystems Engineering}, volume = {195}, year = {2020}, pages = {136{\textendash}151}, abstract = {Non-destructive estimates information on the desired properties of fruit without damaging them. The objective of this work is to present an algorithm for the automatic and non-destructive estimation of four maturity stages (unripe, half-ripe, ripe, or overripe) of Fuji apples (Malus Malus pumila) using both colour and spectral data from fruit. In order to extract spectral and colour data to train a proposed system, 170 samples of Fuji apples were collected. Colour and spectral features were extracted using a CR-400 Chroma Meter colorimeter and a custom set up. The second component of colour space and near infrared (NIR) spectrum data in wavelength ranges of 535{\textendash}560 nm, 835{\textendash}855 nm, and 950{\textendash}975 nm, were used to train the proposed algorithm. A hybrid artificial neural network-simulated annealing algorithm (ANN-SA) was used for classification purposes. A total of 1000 iterations were conducted to evaluate the reliability of the classification process. Results demonstrated that after training the correction classification rate (CCR, accuracy) was, at the best state, 100\% (test set) using both colour and spectral data. The CCR of the four different classifiers were 93.27\%, 99.62\%, 98.55\%, and 99.59\%, for colour features, spectral data wavelength ranges of 535{\textendash}560 nm, 835{\textendash}855 nm, and 950{\textendash}975 nm, respectively, over the test set. These results suggest that the proposed method is capable of the non-destructive estimation of different maturity stages of Fuji apple with a remarkable accuracy, in particular within the 535{\textendash}560 nm wavelength range.}, doi = {https://doi.org/10.1016/j.biosystemseng.2020.04.015}, url = {https://www.sciencedirect.com/science/article/pii/S1537511020301148}, author = {Pourdarbani, Razieh and Sabzi, Sajad and Kalantari, Davood and Karimzadeh, Rouhollah and Ilbeygi, Elham and J I Arribas} } @article {867, title = {An automatic visible-range video weed detection, segmentation and classification prototype in potato field}, journal = {Heliyon}, volume = {6}, year = {2020}, pages = {e03685}, abstract = {Weeds might be defined as destructive plants that grow and compete with agricultural crops in order to achieve water and nutrients. Uniform spray of herbicides is nowadays a common cause in crops poisoning, environment pollution and high cost of herbicide consumption. Site-specific spraying is a possible solution for the problems that occur with uniform spray in fields. For this reason, a machine vision prototype is proposed in this study based on video processing and meta-heuristic classifiers for online identification and classification of Marfona potato plant (Solanum tuberosum) and 4299 samples from five weed plant varieties: Malva neglecta (mallow), Portulaca oleracea (purslane), Chenopodium album L (lamb{\textquoteright}s quarters), Secale cereale L (rye) and Xanthium strumarium (coklebur). In order to properly train the machine vision system, various videos taken from two Marfona potato fields within a surface of six hectares are used. After extraction of texture features based on the gray level co-occurrence matrix (GLCM), color features, spectral descriptors of texture, moment invariants and shape features, six effective discriminant features were selected: the standard deviation of saturation (S) component in HSV color space, difference of first and seventh moment invariants, mean value of hue component (H) in HSI color space, area to length ratio, average blue-difference chrominance (Cb) component in YCbCr color space and standard deviation of in-phase (I) component in YIQ color space. Classification results show a high accuracy of 98\% correct classification rate (CCR) over the test set, being able to properly identify potato plant from previously mentioned five different weed varieties. Finally, the machine vision prototype was tested in field under real conditions and was able to properly detect, segment and classify weed from potato plant at a speed of up to 0.15 m/s.}, doi = {https://doi.org/10.1016/j.heliyon.2020.e03685}, url = {https://www.sciencedirect.com/science/article/pii/S2405844020305302}, author = {Sabzi, Sajad and Yousef Abbaspour-Gilandeh and J I Arribas} } @article {805, title = {Air Infiltration Monitoring using Thermography and Neural Networks}, journal = {Energy and Buildings}, volume = {191}, year = {2019}, month = {05/2019}, pages = {187-199}, chapter = {187}, author = {A Royuela and M A Padilla-Marcos and A Meiss and Pablo Casaseca-de-la-Higuera and J Feij{\'o}-Mu{\~n}oz} } @article {862, title = {An Automatic Non-Destructive Method for the Classification of the Ripeness Stage of Red Delicious Apples in Orchards Using Aerial Video}, journal = {Agronomy}, volume = {9}, year = {2019}, abstract = {The estimation of the ripening state in orchards helps improve post-harvest processes. Picking fruits based on their stage of maturity can reduce the cost of storage and increase market outcomes. Moreover, aerial images and the estimated ripeness can be used as indicators for detecting water stress and determining the water applied during irrigation. Additionally, they can also be related to the crop coefficient (Kc) of seasonal water needs. The purpose of this research is to develop a new computer vision algorithm to detect the existing fruits in aerial images of an apple cultivar (of Red Delicious variety) and estimate their ripeness stage among four possible classes: unripe, half-ripe, ripe, and overripe. The proposed method is based on a combination of the most effective color features and a classifier based on artificial neural networks optimized with genetic algorithms. The obtained results indicate an average classification accuracy of 97.88\%, over a dataset of 8390 images and 27,687 apples, and values of the area under the ROC (receiver operating characteristic) curve near or above 0.99 for all classes. We believe this is a remarkable performance that allows a proper non-intrusive estimation of ripening that will help to improve harvesting strategies.}, doi = {https://doi.org/10.3390/agronomy9020084}, url = {https://www.mdpi.com/2073-4395/9/2/84}, author = {S Sabzi and Yousef Abbaspour-Gilandeh and G Garcia-Mateos and A Ruiz-Canales and J M Molina-Martinez and J I Arribas} } @article {769, title = {Audio-cough event detection based on moment theory}, journal = {Applied Acoustics}, volume = {135}, year = {2018}, pages = {124{\textendash}135}, author = {Monge-{\'A}lvarez, Jes{\'u}s and Hoyos-Barcel{\'o}, Carlos and Dahal, Keshav and Pablo Casaseca-de-la-Higuera} } @article {858, title = {An automatic and non-intrusive hybrid computer vision system for the estimation of peel thickness in Thomson orange}, journal = {Spanish Journal of Agricultural Research}, volume = {16}, year = {2018}, pages = {e0204}, abstract = {Orange peel has important flavor and nutrition properties and is often used for making jam and oil in the food industry. For previous reasons, oranges with high peel thickness are valuable. In order to properly estimate peel thickness in Thomson orange fruit, based on a number of relevant image features (area, eccentricity, perimeter, length/area, blue component, green component, red component, width, contrast, texture, width/area, width/length, roughness, and length) a novel automatic and non-intrusive approach based on computer vision with a hybrid particle swarm optimization (PSO), genetic algorithm (GA) and artificial neural network (ANN) system is proposed. Three features (width/area, width/length and length/area ratios) were selected as inputs to the system. A total of 100 oranges were used, performing cross validation with 100 repeated experiments with uniform random samples test sets. Taguchi{\textquoteright}s robust optimization technique was applied to determine the optimal set of parameters. Prediction results for orange peel thickness (mm) based on the levels that were achieved by Taguchi{\textquoteright}s method were evaluated in several ways, including orange peel thickness true-estimated boxplots for the 100 orange database and various error parameters: the sum square error (SSE), the mean absolute error (MAE), the coefficient of determination (R2), the root mean square error (RMSE), and the mean square error (MSE), resulting in mean error parameter values of R2=0.854{\textpm}0.052, MSE=0.038{\textpm}0.010, and MAE=0.159{\textpm}0.023, over the test set, which to our best knowledge are remarkable numbers for an automatic and non-intrusive approach with potential application to real-time orange peel thickness estimation in the food industry. }, doi = {http://dx.doi.org/10.5424/sjar/2018164-11185}, url = {https://revistas.inia.es/index.php/sjar/article/view/11185}, author = {H Javadikia and S Sabzi and J I Arribas} } @conference {740, title = {ADC-Weighted Joint Registration-Estimation for Cardiac Diffusion Magnetic Resonance Imaging}, booktitle = {Congreso Anual de la Sociedad Espa{\~n}ola de Ingenier{\'\i}a Biom{\'e}dica}, year = {2017}, month = {12/2017}, abstract = {

The purpose of this work is to develop a method for the groupwise registration of diffusion weighted datasets of the heart which automatically provide smooth Apparent Diffusion Coefficient (ADC) estimations, by making use of a novel multimodal scheme. To this
end, we have introduced a joint methodology that simultaneously performs both the alignment of the images and the ADC estimation. In order to promote diffeomorphic transformations and to avoid undesirable noise amplification, we have included appropriate
smoothness constraints for both problems under the same formulation. The implemented multimodal registration metric incorporates the ADC estimation residuals, which are inversely weighted with the b-values to balance the influence of the signal level for each diffusion weighted image. Results show that the joint formulation provides more robust and precise ADC estimations and a significant improvement in the overlap of the contour
of manual delineations along the different b-values. The proposed algorithm is able to effectively deal with the presence of both physiological motion and inherent contrast variability for the different b-value images, increasing accuracy and robustness of the estimation of diffusion parameters for cardiac imaging.

}, author = {Santiago Sanz-Est{\'e}banez and J Royuela-del-Val and Jordi Broncano-Cabrero and Santiago Aja-Fern{\'a}ndez and Carlos Alberola-Lopez} } @article {698, title = {Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy}, journal = {Scientific Reports}, volume = {7}, year = {2017}, abstract = {

Seizure-driven brain damage in epilepsy accumulates over time, especially in the hippocampus, which can lead to sclerosis, cognitive decline, and death. Excitotoxicity is the prevalent model to explain ictal neurodegeneration. Current labeling technologies cannot distinguish between excitotoxicity and hypoxia, however, because they share common molecular mechanisms. This leaves open the possibility that undetected ischemic hypoxia, due to ictal blood flow restriction, could contribute to neurodegeneration previously ascribed to excitotoxicity. We tested this possibility with Confocal Laser Endomicroscopy (CLE) and novel stereological analyses in several models of epileptic mice. We found a higher number and magnitude of NG2+ mural-cell mediated capillary constrictions in the hippocampus of epileptic mice than in that of normal mice, in addition to spatial coupling between capillary constrictions and oxidative stressed neurons and neurodegeneration. These results reveal a role for hypoxia driven by capillary blood flow restriction in ictal neurodegeneration. {\textcopyright} 2017 The Author(s).

}, doi = {10.1038/srep43276}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014072909\&doi=10.1038\%2fsrep43276\&partnerID=40\&md5=e9d3567266bdc360a7addc92be350c8d}, author = {Leal-Campanario, R. and Alarcon-Martinez, L. and Rieiro, H. and Martinez-Conde, S. and Alarcon-Martinez, T. and Zhao, X. and LaMee, J. and Popp, P.J. and Calhoun, M.E. and J I Arribas and Schlegel, A.A. and Di Stasi, L.L. and Rho, J.M. and Inge, L. and Otero-Millan, J. and Treiman, D.M. and Macknik, S.L.} } @conference {600, title = {An Automated Tensorial Classification Procedure for Left Ventricular Hypertrophic Cardiomyopathy}, booktitle = {IWBBIO 2016 (4th International Work-Conference on Bioinformatics and Biomedical Engineering)}, volume = {1}, year = {2016}, month = {2016}, pages = {1-12}, edition = {LNBI 9656}, address = {Granada, Spain}, abstract = {

Cardiovascular diseases are the leading cause of death globally. Therefore, classi cation tools play a major role in prevention and\ treatment of these diseases. Statistical learning theory applied to magnetic resonance imaging has led to the diagnosis of a variety of cardiomyopathies states.\ We propose a two-stage classi cation scheme capable of\ distinguishing between heterogeneous groups of hypertrophic cardiomyopathies and healthy patients.\ A multimodal processing pipeline is employed to estimate robust tensorial descriptors of myocardial mechanical\ properties for both short-axis and long-axis magnetic resonance tagged\ images using the least absolute deviation method. A homomorphic ltering procedure is used to align the cine segmentations to the tagged sequence and provides 3D tensor information in meaningful areas.\ Results\ have shown that the proposed pipeline provides tensorial measurements\ on which classi ers for the study of hypertrophic cardiomyopathies can\ be built with acceptable performance even for reduced samples sets.

}, keywords = {Fuzzy clustering, HARmonic Phase, Homomorphic Filtering, Hypertrophic Cardiomyopathy, Least Absolute Deviation, Magnetic Resonance Tagging, Support Vector Machines}, doi = {10.1007/978-3-319-31744-1 17}, author = {Santiago Sanz-Est{\'e}banez and J Royuela-del-Val and S. Merino-Caviedes and A. Revilla-Orodea and T. Sevilla-Ruiz and Martin-Fernandez, M and Carlos Alberola-Lopez} } @article {627, title = {Adjugate Diffusion Tensors for Geodesic Tractography in White Matter}, journal = {Journal of Mathematical Imaging and Vision}, volume = {54}, year = {2015}, pages = {1{\textendash}14}, abstract = {

One of the approaches in diffusion tensor imaging is to consider a Riemannian metric given by the inverse diffusion tensor. Such a metric is used for geodesic tractography and connectivity analysis in white matter. We propose a metric tensor given by the adjugate rather than the previously proposed inverse diffusion tensor. The adjugate metric can also be employed in the sharpening framework. Tractography experiments on synthetic and real brain diffusion data show improvement for high-curvature tracts and in the vicinity of isotropic diffusion regions relative to most results for inverse (sharpened) diffusion tensors, and especially on real data. In addition, adjugate tensors are shown to be more robust to noise.

}, issn = {1573-7683}, doi = {10.1007/s10851-015-0586-8}, url = {http://dx.doi.org/10.1007/s10851-015-0586-8}, author = {Andrea Fuster and Tom Dela-Haije and Antonio Trist{\'a}n-Vega and Birgit Plantinga and Carl-Fredik Westin and Luc Florack} } @article {448, title = {Anisotropic Diffusion Filter with Memory based on Speckle Statistics for Ultrasound Images}, journal = {IEEE Transactions on image processing}, volume = {24}, year = {2015}, chapter = {345}, doi = {http://dx.doi.org/10.1109/TIP.2014.2371244}, author = {Gabriel Ramos-Llorden and Gonzalo Vegas-S{\'a}nchez-Ferrero and Marcos Martin-Fernandez and Carlos Alberola-Lopez and Santiago Aja-Fern{\'a}ndez} } @article {de2014attention, title = {Attention Deficit/Hyperactivity Disorder and Medication with Stimulants in Young Children: A DTI Study}, journal = {Progress in Neuro-Psychopharmacology and Biological Psychiatry}, volume = {57}, year = {2015}, publisher = {Elsevier}, chapter = {176}, doi = {http://dx.doi.org/10.1016/j.pnpbp.2014.10.014}, author = {Rodrigo de Luis-Garc{\'\i}a and Cab{\'u}s-Pi{\~n}ol, Gemma and Imaz-Roncero, Carlos and Daniel Argibay-Qui{\~n}ones and Gonzalo Barrio-Arranz and Santiago Aja-Fern{\'a}ndez and Carlos Alberola-Lopez} } @proceedings {516, title = {Analysis of coloured noise in received signal strength using the Allan Variance}, volume = {22}, year = {2014}, pages = {994-998}, publisher = {IEEE}, author = {Luo, Chunbo and Pablo Casaseca-de-la-Higuera and McClean, Sally and Parr, Gerard and Grecos, Christos} } @article {martin2014automatic, title = {Automatic detection of wakefulness and rest intervals in actigraphic signals: A data-driven approach}, journal = {Medical engineering \& physics}, volume = {36}, number = {12}, year = {2014}, pages = {1585{\textendash}1592}, publisher = {Elsevier}, author = {Diego Mart{\'\i}n-Mart{\'\i}nez and Pablo Casaseca-de-la-Higuera and Jesus Maria Andres-de-Llano and Jose Ramon Garmendia-Leiza and Susana Alberola-Lopez and Carlos Alberola-Lopez} } @article {ruiz2013advanced, title = {Advanced signal processing methods for biomedical imaging}, journal = {International journal of biomedical imaging}, volume = {2013}, year = {2013}, publisher = {Hindawi Publishing Corporation}, author = {Juan Ruiz-Alzola and Carlos Alberola-Lopez and Carl-Fredik Westin} } @conference {vegas2013anisotropic, title = {Anisotropic diffusion filtering for correlated multiple-coil MRI}, booktitle = {Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE}, year = {2013}, pages = {2956{\textendash}2959}, publisher = {IEEE}, organization = {IEEE}, author = {Gonzalo Vegas-S{\'a}nchez-Ferrero and Gabriel Ramos-Llorden and Rodrigo de Luis-Garc{\'\i}a and Antonio Trist{\'a}n-Vega and Santiago Aja-Fern{\'a}ndez} } @conference {gonzalez2013applying, title = {Applying a parametric approach for the task of nonstationary noise removal with missing information}, booktitle = {Computational Cybernetics (ICCC), 2013 IEEE 9th International Conference on}, year = {2013}, pages = {23{\textendash}28}, publisher = {IEEE}, organization = {IEEE}, author = {Luis Gonz{\'a}lez-Jaime and Nachtegeal, Mike and Kerre, Etienne and Gonzalo Vegas-S{\'a}nchez-Ferrero and Santiago Aja-Fern{\'a}ndez} } @conference {444, title = {Assessment of the fibrotic myocardial tissue mechanics by image processing}, booktitle = {Computing in Cardiology Conference (CinC), 2013}, year = {2013}, publisher = {IEEE}, organization = {IEEE}, author = {Lucilio Cordero-Grande and T. Sevilla-Ruiz and Revilla, Ana and Marcos Martin-Fernandez and Carlos Alberola-Lopez} } @conference {de2013atlas, title = {Atlas-based segmentation of white matter structures from DTI using tensor invariants and orientation}, booktitle = {Engineering in Medicine and Biology Society (EMBC), 2013 35th Annual International Conference of the IEEE}, year = {2013}, pages = {503{\textendash}506}, publisher = {IEEE}, organization = {IEEE}, author = {Rodrigo de Luis-Garc{\'\i}a and Gonzalo Vegas-S{\'a}nchez-Ferrero and Santiago Aja-Fern{\'a}ndez and Carlos Alberola-Lopez} } @conference {vegas2012anisotropic, title = {Anisotropic LMMSE denoising of MRI based on statistical tissue models}, booktitle = {Biomedical Imaging (ISBI), 2012 9th IEEE International Symposium on}, year = {2012}, pages = {1519{\textendash}1522}, publisher = {IEEE}, organization = {IEEE}, author = {Gonzalo Vegas-S{\'a}nchez-Ferrero and Antonio Trist{\'a}n-Vega and Santiago Aja-Fern{\'a}ndez and Marcos Martin-Fernandez and Cesar Palencia and Deriche, Rachid} } @conference {casaseca2012automatic, title = {Automatic diagnosis of ADHD based on multichannel nonlinear analysis of actimetry registries}, booktitle = {Engineering in Medicine and Biology Society (EMBC), 2012 Annual International Conference of the IEEE}, year = {2012}, pages = {4204{\textendash}4207}, publisher = {IEEE}, organization = {IEEE}, author = {Pablo Casaseca-de-la-Higuera and Diego Mart{\'\i}n-Mart{\'\i}nez and Susana Alberola-Lopez and Jesus Maria Andres-de-Llano and L{\'o}pez-Villalobos, Jos{\'e} Antonio and JR Garmendia-Leiza and Carlos Alberola-Lopez} } @proceedings {586, title = {Algoritmo de Compresi{\'o}n de Se{\~n}ales de ECG basado en un Modelo de S{\'\i}ntesis. An{\'a}lisis Comparativo}, volume = {29}, year = {2011}, pages = {733-736}, address = {C{\'a}ceres, Spain}, author = {V{\'\i}ctor Mart{\'\i}nez-Mart{\'\i}nez and Pablo Casaseca-de-la-Higuera and Marcos Martin-Fern{\'a}ndez and Carlos Alberola-Lopez} } @article {193, title = {Anomaly detection in network traffic based on statistical inference and alpha-stable modeling}, journal = {Dependable and Secure Computing, IEEE Transactions on}, volume = {8}, year = {2011}, pages = {494{\textendash}509}, author = {Federico Simmross-Wattenberg and Juan Ignacio Asensio-P{\'e}rez and Pablo Casaseca-de-la-Higuera and Marcos Martin-Fernandez and Yannis A Dimitriadis and Carlos Alberola-Lopez} } @proceedings {576, title = {Automatic diagnosis of ADHD based on nonlinear analysis of actimetry registries}, volume = {32}, year = {2011}, pages = {685-688}, address = {Prague, Czech Rep.}, keywords = {ADHD, ADHD automatic diagnosis, Activity/Rest Detection, Attention-Deficit Hyperactivity Disorder, Automatic Diagnosis System, Central Tendency Measure, Feature extraction, Histograms, Indexes, Noise, Pediatrics, Regularity Assessment, Sleep, USA Councils, Wrist, actimetry registries, adolescence, automatic activity/rest detection filter, biomedical measurement, childhood, feature extraction module, medical disorders, medical signal processing, mental health problem, neurophysiology, nonlinear analysis, nonlinear regularity quantification, paediatrics, pathology, signal processing methods}, author = {Diego Mart{\'\i}n-Mart{\'\i}nez and Pablo Casaseca-de-la-Higuera and Susana Alberola-Lopez and L{\'o}pez-Villalobos, J.A. and Ruiz, F.C. and Jesus Maria Andres-de-Llano and Jose Ramon Garmendia-Leiza and Julio Ardura-Fernández} } @article {aja2010background, title = {About the background distribution in MR data: a local variance study}, journal = {Magnetic resonance imaging}, volume = {28}, number = {5}, year = {2010}, pages = {739{\textendash}752}, publisher = {Elsevier}, author = {Santiago Aja-Fern{\'a}ndez and Gonzalo Vegas-S{\'a}nchez-Ferrero and Antonio Trist{\'a}n-Vega} } @article {cardenes2010analysis, title = {Analysis of the pyramidal tract in tumor patients using diffusion tensor imaging}, journal = {NeuroImage}, volume = {50}, number = {1}, year = {2010}, pages = {27{\textendash}39}, publisher = {Elsevier}, author = {Rub{\'e}n C{\'a}rdenes-Almeida and Emma Mu{\~n}oz-Moreno and Sarabia-Herrero, Rosario and Rodr{\'\i}guez-Velasco, Margarita and Juan Jos{\'e} Fuertes-Alija and Marcos Martin-Fernandez} } @article {423, title = {Automatic bayesian classification of healthy controls, bipolar disorder, and schizophrenia using intrinsic connectivity maps from fMRI data}, journal = {IEEE Transactions on Biomedical Engineering}, volume = {57}, year = {2010}, pages = {2850-2860}, abstract = {

We present a method for supervised, automatic, and reliable classification of healthy controls, patients with bipolar disorder, and patients with schizophrenia using brain imaging data. The method uses four supervised classification learning machines trained with a stochastic gradient learning rule based on the minimization of KullbackLeibler divergence and an optimal model complexity search through posterior probability estimation. Prior to classification, given the high dimensionality of functional MRI (fMRI) data, a dimension reduction stage comprising two steps is performed: first, a one-sample univariate t-test mean-difference Tscore approach is used to reduce the number of significant discriminative functional activated voxels, and then singular value decomposition is performed to further reduce the dimension of the input patterns to a number comparable to the limited number of subjects available for each of the three classes. Experimental results using functional brain imaging (fMRI) data include receiver operation characteristic curves for the three-way classifier with area under curve values around 0.82, 0.89, and 0.90 for healthy control versus nonhealthy, bipolar disorder versus nonbipolar, and schizophrenia patients versus nonschizophrenia binary problems, respectively. The average three-way correct classification rate (CCR) is in the range of 70\%-72\%, for the test set, remaining close to the estimated Bayesian optimal CCR theoretical upper bound of about 80\%, estimated from the one nearest-neighbor classifier over the same data. {\^A}{\textcopyright} 2010 IEEE.

}, keywords = {Algorithms, Artificial Intelligence, Bayes Theorem, Bayesian learning, Bayesian networks, Biological, Brain, Case-Control Studies, Classifiers, Computer-Assisted, Diseases, Functional MRI (fMRI), Humans, Learning machines, Learning systems, Magnetic Resonance Imaging, Models, Operation characteristic, Optimization, ROC Curve, Reproducibility of Results, Signal Processing, Singular value decomposition, Statistical tests, Stochastic models, Student t test, area under the curve, article, bipolar disorder, classification, controlled study, functional magnetic resonance imaging, human, machine learning, major clinical study, neuroimaging, patient coding, receiver operating characteristic, reliability, schizophrenia}, issn = {00189294}, doi = {10.1109/TBME.2010.2080679}, url = {http://www.scopus.com/inward/record.url?eid=2-s2.0-78649311169\&partnerID=40\&md5=d3b90f1a3ee4ef209d131ef986e142db}, author = {J I Arribas and V D Calhoun and T Adali} } @article {garmendia2009acute, title = {Acute myocardial infarction circadian rhythm in a geriatric population in Castilla y Leon}, journal = {Journal of the American Geriatrics Society}, volume = {57}, number = {7}, year = {2009}, pages = {1312{\textendash}1313}, publisher = {Wiley Online Library}, author = {Jose Ramon Garmendia-Leiza and Jesus Maria Andres-de-Llano and Julio Ardura-Fernández and Juan Bautista Lopez-Messa and MD Aguilar-Garcia and Carlos Alberola-Lopez} } @article {martin2009addendum, title = {Addendum to {\textquotedblleft}Sequential anisotropic multichannel Wiener filtering with Rician bias correction applied to 3D regularization of DWI data{\textquotedblright}[Medical Image Analysis 13 (2009) 19{\textendash}35]}, journal = {Medical image analysis}, volume = {13}, number = {6}, year = {2009}, pages = {910}, publisher = {Elsevier}, author = {Marcos Martin-Fernandez and Emma Mu{\~n}oz-Moreno and Cammoun, Leila and J-P Thiran and Carl-Fredik Westin and Carlos Alberola-Lopez} } @article {martin2009automatic, title = {Automatic articulated registration of hand radiographs}, journal = {Image and Vision Computing}, volume = {27}, number = {8}, year = {2009}, pages = {1207{\textendash}1222}, publisher = {Elsevier}, author = {Miguel Angel Martin-Fernandez and Rub{\'e}n C{\'a}rdenes-Almeida and Emma Mu{\~n}oz-Moreno and Rodrigo de Luis-Garc{\'\i}a and Marcos Martin-Fernandez and Carlos Alberola-Lopez} } @article {aja2009automatic, title = {Automatic noise estimation in images using local statistics. Additive and multiplicative cases}, journal = {Image and Vision Computing}, volume = {27}, number = {6}, year = {2009}, pages = {756{\textendash}770}, publisher = {Elsevier}, author = {Santiago Aja-Fern{\'a}ndez and Gonzalo Vegas-S{\'a}nchez-Ferrero and Marcos Martin-Fernandez and Carlos Alberola-Lopez} } @conference {478, title = {Automatic segmentation of white matter structures from DTI using tensor invariants and tensor orientation}, booktitle = {Proc. Intl. Soc. Mag. Reson. Med}, year = {2009}, author = {Rodrigo de Luis-Garc{\'\i}a and Lopez, C Alberola and Kindlmann, G and Carl-Fredik Westin} } @conference {de2007p6d, title = {Analysis of Ultrasound Images Based on Local Statistics. Application to the Diagnosis of Developmental Dysplasia of the Hip}, booktitle = {Ultrasonics Symposium, 2007. IEEE}, year = {2007}, pages = {2531{\textendash}2534}, publisher = {IEEE}, organization = {IEEE}, author = {Rodrigo de Luis-Garc{\'\i}a and Santiago Aja-Fern{\'a}ndez and Rub{\'e}n C{\'a}rdenes-Almeida and Marcos Martin-Fernandez and Carlos Alberola-Lopez} } @article {lopez2005age, title = {Age as modifying factor of circadian rhythm of acute myocardial infarction}, journal = {MEDICINA INTENSIVA}, volume = {29}, number = {9}, year = {2005}, pages = {455}, publisher = {IDEPSA}, author = {Juan Bautista Lopez-Messa and JR Garmendia-Leiza and MD Aguilar-Garcia and Jes{\'u}s Mar{\'\i}a And De Llano and Julio Ardura-Fernández and Carlos Alberola-Lopez} } @conference {martin2005articulated, title = {Articulated registration: Elastic registration based on a wire-model}, booktitle = {Medical Imaging}, year = {2005}, pages = {182{\textendash}191}, publisher = {International Society for Optics and Photonics}, organization = {International Society for Optics and Photonics}, author = {Miguel Angel Martin-Fernandez and Emma Mu{\~n}oz-Moreno and Marcos Martin-Fernandez and Carlos Alberola-Lopez} } @article {martin2005approach, title = {An approach for contour detection of human kidneys from ultrasound images using Markov random fields and active contours}, journal = {Medical Image Analysis}, volume = {9}, number = {1}, year = {2005}, pages = {1{\textendash}23}, publisher = {Elsevier}, author = {Marcos Martin-Fernandez and Carlos Alberola-Lopez} } @conference {martin2003automatic, title = {Automatic bone age assessment: A registration approach}, booktitle = {Medical Imaging 2003}, year = {2003}, pages = {1765{\textendash}1776}, publisher = {International Society for Optics and Photonics}, organization = {International Society for Optics and Photonics}, author = {Miguel Angel Martin-Fernandez and Marcos Martin-Fernandez and Carlos Alberola-Lopez} }