Laboratorio de Procesado de Imagen

(Image Processing Lab)
E.T.S.I. Telecomunicación
Campus Miguel Delibes s/n
Universidad de Valladolid
47011 Valladolid, Spain

Gray matter morphometry alterations in migraine

[23 Nov 2020]

A paper about the assessment of gray matter morphometry parameters in migraine patients, Gray Matter Structural Alterations in Chronic and Episodic Migraine: A Morphometric Magnetic Resonance Imaging Study, has been published in Pain Medicine. This article has been written by Álvaro Planchuelo-Gómez, Santiago Aja-Fernández and Rodrigo de Luis-García, in collaboration with the Headache Unit and the Department of Radiology of the Clinical Hospital of Valladolid. The findings of this research suggest that there are widespread gray matter alterations in migraine. Chronic migraine would be a distinct entity with respect to a high frequency episodic migraine and the surface area would be a proper biomarker to identify it. The results of this study suggest that the pattern of differences between healthy controls and episodic migraine patients is qualitatively different from that occurring between episodic and chronic migraine patients. The article is available here:

New dMRI methodology uncovers additional alterations in migraine

[10 Nov 2020]

AMURA (, the new tool developed by LPI members, has been used to compare diffusion measures in patients with episodic and chronic migraine and healthy controls using clinical routine diffusion MRI acquisition parameters. Using AMURA, additional statistically significant differences were found with respect to the diffusion tensor imaging (DTI) descriptors. This article demonstrates that AMURA can provide additional results with respect to DTI to uncover white matter alterations in migraine, even in suboptimal conditions for the tool with a single low b-value.
The new paper, entitled "Alternative Microstructural Measures to Complement Diffusion Tensor Imaging in Migraine Studies with Standard MRI Acquisition", has been published in Brain Sciences. The article is available here (Open Access):

LPI research on COVID-19

[25 May 2020]

The first LPI article about the psychological impact of the COVID-19 confinement has been published. This article has been made in collaboration with the Department of Psychology of the University of Valladolid. The main finding was that students from Arts & Humanities and Social Sciences and Law areas showed higher psychological impact, especially compared to the students from the Engineering & Architecture field (click on the title of the article for more highlights). The article is freely available until 11 July in the following link: